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Product Information:

S-309309

S-309309 is an orally active and selective MGAT2 inhibitor. S-309309 can be used in metabolism-related research.

Cat. No.: EX-A13241    Purity: >98%
Chemical
Chemical structure of S-309309


For research only, Do not use for Human!

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CAS No.2267352-04-3
Purity>98%
FormulaC23H21F2N5O5S
Mol Weight517.505
ColorWhite to off-white
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Miyano T, et al. The Continuous and Reversible Transformation of the Polymorphs of an MGAT2 Inhibitor (S-309309) from the Anhydrate to the Hydrate in Response to Relative Humidity. Pharmaceutics. 2024 Jul 17;16(7):949.

[2]. YOSHIKI RYO, et al. 1649-P: S-309309, a Novel MGAT2 Inhibitor, Enhances Intestinal Fatty Acid Beta Oxidation and Provides Metabolic Benefits in DIO Mice. Diabetes, 2024, 73(Supplement_1).

CoACoA of S-309309
Smiles:FC1=C2[C@@]3(CC=4C(C(=O)N3)=C(NC(CS(C)(=O)=O)=O)N(N4)C5=CC=C(C)C=N5)CCOC2=CC(F)=C1

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