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Product Information:

RXR agonist 1

RXR agonist 1 (Compound 33) is a highly selective RXR agonist, with EC50s of 9 nM, 18 nM, and 11 nM for RXRα, RXRβ, and RXRγ, respectively. RXR agonist 1 binds to RXR with high affinity (Kd = 0.03 μM).

Cat. No.: EX-A13689    Purity: >98%
Chemical
Chemical structure of RXR agonist 1


For research only, Do not use for Human!

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CAS No.3033207-97-2
Purity>98%
FormulaC18H20ClN3O3
Mol Weight361.823
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lewandowski M, et al. Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties. J Med Chem. 2024 Jan 18.

CoACoA of RXR agonist 1
Smiles:O=C(O)CCOC1=NC(Cl)=CC(=N1)N2C=3C=CC=CC3C(C)(C)CC2

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