(RXR)4XB

(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models.


Cat. No.: EX-A13427	Purity: >98%

	Chemical structure of (RXR)4XB

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	650	contact us for price and avail
100mg	922	contact us for price and avail
500mg	2982	contact us for price and avail
1g	get quote	contact us for price and avail

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CAS No.	879010-15-8
Purity	>98%
Formula	C81H158N38O15
Mol Weight	1904.3668
Color	White to off-white
State	Solid
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Howard JJ, et al., Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e01938-16.
CoA	CoA of (RXR)4XB

Smiles:	[C@@H](NC([C@@H](NC(CCCCCNC([C@@H](NC([C@@H](NC(CCCCCNC([C@H](CCCNC(=N)N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)(C(NCCCCCC(N[C@H](C(N[C@H](C(NCCCCCC(N[C@H](C(NCCCCCC(NCCC(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N


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