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Product Information:

RWJ 50271

RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion.

Cat. No.: EX-A5356    Purity: >98%
Chemical
Chemical structure of RWJ 50271


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg485In-stock
250mg785In-stock
5gget quote


SynonymsRWJ50271
CAS No.162112-37-0
Purity>98%
FormulaC18H17F3N4O2S
Mol Weight410.413
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 250 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sanfilippo PJ, et al. Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J Med Chem. 1995 Mar 31;38(7):1057-9.

CoACoA of RWJ 50271

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