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Product Information:

RTC-5

RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling .

Cat. No.: EX-A16692    Purity: >98%
Chemical
Chemical structure of RTC-5


For research only, Do not use for Human!

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SynonymsTRC-382
CAS No.1423077-49-9
Purity>98%
FormulaC24H22ClF3N2O3S
Mol Weight510.956
Colorwhite to off-white
Statesolid
SolubilityDMSO : 15 mg/mL (29.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent-20°C, 1 year
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kastrinsky DB, et al. Reengineered tricyclic anti-cancer agents. Bioorg Med Chem. 2015 Oct 1;23(19):6528-34.

CoACoA of RTC-5
Smiles:O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O

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