RT2

RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide, with main targets including lipopolysaccharide (LPS) on the bacterial surface and intracellular DNA. RT2 binds to bacterial surface LPS, and interacts with cytoplasmic membrane phospholipids, enabling it to rapidly penetrate the bacterial cell membrane and enter the cell, and then bind to components such as DNA in the cytoplasmic membrane, thereby exerting antibacterial effects. RT2 is promising for research of acute and chronic infections caused by planktonic bacteria .


Cat. No.: EX-A15944	Purity: >98%

	Chemical structure of RT2

For research only, Do not use for Human!

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CAS No.	1539295-33-4
Purity	>98%
Formula	C126H165N39O20
Mol Weight	2545.9077
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Anunthawan T, et al. Cationic amphipathic peptides KT2 and RT2 are taken up into bacterial cells and kill planktonic and biofilm bacteria. Biochim Biophys Acta. 2015 Jun;1848(6):1352-8.
CoA	CoA of RT2

Smiles:	C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H


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