RS47

RS47 is a potent and specific inhibitor of the non-canonical NF-κB signaling pathway through disrupting RelB binding to its target DNA with a Kd values of 1.1 μM. It is shown to inhibit colorectal cancer (CRC) cells and B lymphoma growth, holds potential as a research tool for targeting cancers driven by hyperactive non-canonical NF-κB signaling.


Cat. No.: EX-A12420	Purity: >98%

	Chemical structure of RS47

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	475	In-stock
50mg	740	In-stock
100mg	1200	In-stock
250g	2300	In-stock
500mg	3680	In-stock
1g	5440	In-stock

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Synonyms	RelB inhibitor RS47
CAS No.	301655-16-3
Purity	>98%
Formula	C18H18N4O2S
Mol Weight	354.426
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li, Cuifeng et al. Development of RelB-targeting small-molecule inhibitors of non-canonical NF-κB signaling with antitumor efficacy Molecular Therapy, Volume 33, Issue 4, 1519 - 1534
CoA	CoA of RS47

Smiles:	OC1=CC=C(O)C(=C1)C(=NNC=2N=CN=C3SC4=C(C32)CCCC4)C


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