RRD-251

RRD-251 is an inhibitor of retinoblastoma tumor suppressor protein (Rb)-Raf-1 interaction, with potent anti-proliferative, anti-angiogenic and anti-tumor activities .


Cat. No.: EX-A10765	Purity: >98%

	Chemical structure of RRD-251

For research only, Do not use for Human!

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CAS No.	72214-67-6
Purity	>98%
Formula	C8H9Cl3N2S
Mol Weight	271.594
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Sandeep Singh, et al. Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine. Mol Cancer Ther. 2010 Dec; 9(12): 3330–3341.
CoA	CoA of RRD-251

Smiles:	NC(SCC1=CC=C(Cl)C=C1Cl)=N.[H]Cl


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