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Product Information:

RR-11055

RR-11055 (Compound 8) is a ligand for E3 ligase, that exhibits an affinity with cereblon with Ki of 0.38 μM. RR-11055 can be used for synthesis of PROTAC Degrader ERD-1233.

Cat. No.: EX-A15490    Purity: >98%
Chemical
Chemical structure of RR-11055


For research only, Do not use for Human!

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CAS No.3026009-09-3
Purity>98%
FormulaC18H20N4O4
Mol Weight356.3758
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Acharyya RK, et al., Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67(21):19010-19037.

CoACoA of RR-11055
Smiles:O=C1C2=CC=C(N3[C@@](CNCC3)([H])CO4)C4=C2CN1[C@@H]5C(NC(CC5)=O)=O

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