Rp-8-pCPT-Cyclic GMPS sodium salt

Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner[1][2].


Cat. No.: EX-A14739	Purity: >98%

	Chemical structure of Rp-8-pCPT-Cyclic GMPS sodium salt

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Synonyms	Rp-8-pCPT-cGMPS
CAS No.	208445-07-2
Purity	>98%
Formula	C16H14ClN5NaO6PS2
Mol Weight	525.859
Color	White to off-white
State	Solid
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Liu S, et al., cGMP and cGMP-dependent protein kinase I pathway in dorsal root ganglia contributes to bone cancer pain in rats. Spine (Phila Pa 1976). 2014 Sep 1;39(19):1533-41. [2]. Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64.
CoA	CoA of Rp-8-pCPT-Cyclic GMPS sodium salt

Smiles:	C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(C(=O)NC(=N4)N)N=C3SC5=CC=C(C=C5)Cl)O)OP(=S)(O1)[O-].[Na+]


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