RP 67580

RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation[1].


Cat. No.: EX-A14752	Purity: >98%

	Chemical structure of RP 67580

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	680	Inquire
500mg	1480	Inquire
1g	2280	Inquire

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CAS No.	135911-02-3
Purity	>98%
Formula	C29H30N2O2
Mol Weight	438.5607
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Garret C, et al. Pharmacological properties of a potent and selective nonpeptide substance P antagonist. Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10208-12.
CoA	CoA of RP 67580

Smiles:	COC1=CC=CC=C1CC(=N)N2C[C@H]3[C@@H](C2)C(CCC3=O)(C4=CC=CC=C4)C5=CC=CC=C5


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