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Product Information:

RORγt-IN-9a

RORγt inhibitor 4 (Compound 9a) is an orally active and a CNS-penetrating RORγt inhibitor. RORγt inhibitor 4 improves experimental autoimmune encephalomyelitis.

Cat. No.: EX-A13675    Purity: >98%
Chemical
Chemical structure of RORγt-IN-9a


For research only, Do not use for Human!

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SynonymsROR(gamma)t-IN-9a
CAS No.1426803-07-7
Purity>98%
FormulaC22H16Cl2F3NO4S
Mol Weight518.333
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wang Y, et al. Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors. ACS Med Chem Lett. 2015 May 26;6(7):787-92.

CoACoA of RORγt-IN-9a
Smiles:O=C(NC1=CC(Cl)=C(C2=CC=CC=C2OC(F)(F)F)C(Cl)=C1)CC3=CC=C(S(=O)(C)=O)C=C3

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