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Product Information:

RORγ agonist 1

RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity.

Cat. No.: EX-A13828    Purity: >98%
Chemical
Chemical structure of RORγ agonist 1


For research only, Do not use for Human!

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CAS No.2260631-91-0
Purity>98%
FormulaC29H27ClF4N2O4S
Mol Weight611.047
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lu B, et al. Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity. J Med Chem. 2021 Oct 28;64(20):14983-14996.

CoACoA of RORγ agonist 1
Smiles:FCCN1C2=CC=C(C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CO)=O)C=C2C=C1CC4=C(C=C(C=C4)Cl)C(F)(F)F

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