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Product Information:

Roblitinib

Roblitinib (FGF-401) is an orally active and highly selective FGFR4 inhibitor with an IC50 of 1.9 nM. Roblitinib has antitumor activity.

Cat. No.: EX-A1341    Purity: >98%
Chemical
Chemical structure of Roblitinib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg350In-stock
250mg450In-stock
500mg698In-stock
1g898In-stock
2g1500In-stock


SynonymsFGF401
CAS No.1708971-55-4
Purity>98%
FormulaC25H30N8O4
Mol Weight506.5569
Colorwhite to off-white
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nicole Buschmann, et al. Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO2015059668A1.

[2]. Robin A Fairhurst, et al. Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4. J Med Chem. 2020 Nov 12;63(21):12542-12573.

CoACoA of Roblitinib
Smiles:COCCNC1=C(C=NC(NC(=O)N2CCCC3=CC(CN4CCN(C)CC4=O)=C(C=O)N=C23)=C1)C#N

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