RNA polymerase-IN-4

RNA polymerase-IN-4 is a RNA polymerase inhibitor with an EC50 of 22.81 nM. RNA polymerase-IN-4 exhibits potent anti-influenza virus activity (EC50 = 3.76 nM), relatively low cytotoxicity (CC50 = 29.91 μM). RNA polymerase-IN-4 can be used for the research of infection, such as influenza virus infection .


Cat. No.: EX-A16463	Purity: >98%

	Chemical structure of RNA polymerase-IN-4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
25mg	get quote

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CAS No.	3040910-48-0
Purity	>98%
Formula	C28H25F2N3O4S
Mol Weight	537.578
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].He J, et al. Discovery of a spirocyclic influenza RNA-dependent RNA polymerase inhibitor. Bioorg Chem. 2025 Oct 17;166:109109.
CoA	CoA of RNA polymerase-IN-4

Smiles:	O=C1N2[C@@](N(N3C1=C(O)C(=O)C=C3)[C@H]4C=5C(CSC=6C4=CC=CC6)=C(F)C(F)=CC5)(CC7(C2)CCOCC7)[H]


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