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Product Information:

RMC-4550

RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM.

Cat. No.: EX-A3075    Purity: >98%
Chemical
Chemical structure of RMC-4550


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg832In-stock
500mg1350In-stock
1g2350In-stock
5g6950In-stock


CAS No.2172651-73-7
Purity>98%
FormulaC21H26Cl2N4O2
Mol Weight437.363
Statesolid powder
SolubilityDMSO >100mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nichols RJ, et al. RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers. Nat Cell Biol. 2018 Sep;20(9):1064-1073.

CoACoA of RMC-4550
Smiles:C[C@H]1[C@H](C2(CCN(CC2)C3=NC(=C(N=C3CO)C4=C(C(=CC=C4)Cl)Cl)C)CO1)N

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