RMC-0331

RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction.


Cat. No.: EX-A5615	Purity: >98%

	Chemical structure of RMC-0331

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	285	In-stock
25mg	585	In-stock
50mg	885	In-stock
100mg	1185	In-stock
250mg	1885	In-stock

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Synonyms	RM-023
CAS No.	2488788-52-7
Purity	>98%
Formula	C22H25ClF3N5O3
Mol Weight	499.914
Color	White to yellow
State	solid powder
Solubility	Soluble in DMSO 125 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Andreas Buckl, et al. Discovery of a Potent, Selective and Orally Bioavailable SOS1 Inhibitor, RMC-0331 (RM-023), an in vivo Tool Compound that Blocks RAS Activation via Disruption of the RAS-SOS1 Interaction.
CoA	CoA of RMC-0331

Smiles:	COC1(C(N2CC3=NC(Cl)=NC(N[C@@H](C4=CC(C(F)(F)F)=CC(N)=C4)C)=C3C2)=O)CCOCC1


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