RM2

RM2 is a GRPr antagonist. RM2 selectively binds to GRPr, blocks agonist-induced receptor internalization, and inhibits agonist-triggered intracellular calcium mobilization. RM2 can be used in studies related to prostate cancer .


Cat. No.: EX-A17275	Purity: >98%

	Chemical structure of RM2

For research only, Do not use for Human!

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Synonyms	L-Leucinamide,N-[2-[4-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]amino]-1-piperidinyl]acetylChemicalbook]-D-phenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-
CAS No.	1186600-65-6
Purity	>98%
Formula	C78H118N20O19
Mol Weight	1639.894
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mansi R, et al. Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours. Eur J Nucl Med Mol Imaging. 2011;38(1):97-107.
CoA	CoA of RM2

Smiles:	C([C@H](NC([C@@H](NC([C@@H](CC1=CC=CC=C1)NC(CN2CCC(NC(CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)=O)CC2)=O)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC4=CN=CN4)C(N[C@H]([C@H](CC(N[C@@H](CC(C)C)C(N)=O)=O)O)CC(C)C)=O)=O)=O)[C@H](C)C)=O)C)=O)C=5C=6C(NC5


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