RANK-derived TRAF6 inhibitor

RANK-derived TRAF6 inhibitor is a TRAF6 inhibitor peptide that blocks the interaction of TRAF6 and LMP1 with an IC50 of 177 nM. RANK-derived TRAF6 inhibitor causes a severe reduction in cell viability in the LMP1-dependent lymphoblastoid cell lines (LCLs) .


Cat. No.: EX-A16102	Purity: >98%

	Chemical structure of RANK-derived TRAF6 inhibitor

For research only, Do not use for Human!

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CAS No.	1393741-66-6
Purity	>98%
Formula	C158H250N48O40S
Mol Weight	3494.038
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Fabian Giehler, et al. Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex. Nat Commun. 2024 Jan 10;15(1):414.
CoA	CoA of RANK-derived TRAF6 inhibitor

Smiles:	C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)CCC(O)=O


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