Rac-SGR-1505

Rac-SGR-1505 is the racemic mixture of SGR-1505. SGR-1505 is an oral small molecule MALT1 inhibitor with anti-proliferative and antitumor activity.SGR-1505 inhibits MALT1 enzymatic activity to modulate NF-κB pathway gene expression. SGR-1505 induces modulation of cell cycle, DNA damage, and apoptosis-related genes in in vivo tumor samples. SGR-1505 exerts tumorostatic and regressive activity in ABC-DLBCL xenograft models.


Cat. No.: EX-A16979	Purity: >98%

	Chemical structure of Rac-SGR-1505

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	756	in-stock
10mg	1085	in-stock
25mg	1885	in-stock
50mg	2985	in-stock
100mg	get quote	in-stock
500mg	get quote	in-stock

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Synonyms	Rac-Zilemaltib
Synonyms 2	Rac-SDCC-3116
CAS No.	2661482-83-1
Purity	>98%
Formula	C18H12ClF4N9O
Mol Weight	481.794
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Adam Olszewski MD, et al. A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of Sgr-1505 As Monotherapy in Subjects with Mature B-Cell Malignancies.Blood. Volume 142, Supplement 1, 2 November 2023, Page 3102.
CoA	CoA of Rac-SGR-1505

Smiles:	O=C(NC1=CN=C(C(Cl)=C1)N2N=CC=N2)N3C=4C=NC5=CC(F)=NN5C4C(C)(C3)C(F)(F)F


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