Rac-M4076

(Rac)-Lartesertib ((Rac)-M4076) is an isoform of Lartesertib. Lartesertib (M4076) is an inhibitor of the serine/threonine protein kinase ATM with high potency. Lartesertib can inhibit the growth of multiple hematopoietic cell lines. Additionally, when combined with the ATR inhibitor Tuvusertib, Lartesertib can promote the death of tumor cells, activate the immune signaling pathway, and exhibit anti-tumor activity.


Cat. No.: EX-A6934	Purity: >98%

	Chemical structure of Rac-M4076

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	700	In-stock
100mg	1100	In-stock
250mg	1900	In-stock
500mg	2900	In-stock
1g	4200	In-stock

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Synonyms	(Rac)-Lartesertib
CAS No.	2020089-41-0
Purity	>98%
Formula	C23H21FN6O3
Mol Weight	448.4496
State	solid powder
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mukker J K, et al. In vitro evaluation of myelosuppressive effects of ATRi tuvusertib and ATMi lartesertib (M4076), alone and in combination. Cancer Research, 2024, 84(6_Supplement): 7186-7186. [2]. Laaber K, et al. Combined inhibition of ATR and ATM with tuvusertib and lartesertib (M4076) impacts the tumor microenvironment. Cancer Research, 2024, 84(6_Supplement): 5617-5617.
CoA	CoA of Rac-M4076


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