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Product Information:

(R)-SKBG-1

(R)-SKBG-1 is an RNA-binding protein NONO inhibitor. (R)-SKBG-1 suppresses androgen receptor expression with IC50s of 3.1 μM and 5.5 μM against AR-FL mRNA and AR-V7 mRNA, respectively.

Cat. No.: EX-A8139    Purity: >98%
Chemical
Chemical structure of (R)-SKBG-1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg1685Inquire
1g2585Inquire
2gget quoteInquire
3g4900Inquire
5gget quoteInquire


CAS No.2955634-67-8
Purity>98%
FormulaC22H26ClN3O6S
Mol Weight495.976
ColorWhite to yellow
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kathman SG, et al. Remodeling oncogenic transcriptomes by small molecules targeting NONO. Nat Chem Biol. 2023 Jul;19(7):825-836.

CoACoA of (R)-SKBG-1
Smiles:O=C([C@@H]1N(S(=O)(C2=CC=C(OC)C=C2)=O)CCN(C(CCl)=O)C1)NCC3=CC=C(OC)C=C3

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