R-7128

Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.


Cat. No.: EX-A5262	Purity: >98%

	Chemical structure of R-7128

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	650	In-stock
100mg	950	In-stock
200mg	1350	In-stock
500mg	1950	In-stock

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Synonyms	Mericitabine
Synonyms 2	RG 7128
CAS No.	940908-79-2
Purity	>98%
Formula	C18H26FN3O6
Mol Weight	399.4139
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Le Pogam S, et al. Characterization of HCV quasispecies dynamics upon short term dual-therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS3/4 protease inhibitor danoprevir. Antimicrob Agents Chemother. 2012 Nov;56(11):5494-5 [2]. Guedj J, et al. Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128). Hepatology. 2012 Apr;55(4):1030-7.
CoA	CoA of R-7128

Smiles:	O=C1N=C(C=CN1[C@@H]([C@@](C)([C@@H]2OC(C(C)C)=O)F)O[C@@H]2COC(C(C)C)=O)N


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