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Product Information:

R-268712

R-268712 is a potent and selective inhibitor of ALK5 with an IC50 of 2.5 nM.

Cat. No.: EX-A2776    Purity: >98%
Chemical
Chemical structure of R-268712


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg438in_stock
500mg694in_stock
1g1134in_stock
2g1840in_stock
3g2137in_stock
5g2827in_stock


CAS No.879487-87-3
Purity>98%
FormulaC20H18FN5O
Mol Weight363.3882
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Terashima H, et al. R-268712, an orally active transforming growth factor-β type I receptor inhibitor, prevents glomerular sclerosis in a Thy1 nephritis model. Eur J Pharmacol. 2014 Jul 5;734:60-6.

CoACoA of R-268712
Smiles:CC1=CC=CC(=N1)C1=C(C=NN1)C1=CC(C2=CN(CCO)N=C2)=C(F)C=C1

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