Quilseconazole

Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes.


Cat. No.: EX-A8336	Purity: >98%

	Chemical structure of Quilseconazole

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	534	in_stock
50mg	841	in_stock
100mg	1286	in_stock
250mg	2196	in_stock
500mg	3449	in_stock

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Synonyms	VT-1129
CAS No.	1340593-70-5
Purity	>98%
Formula	C22H14F7N5O2
Mol Weight	513.3677
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lockhart SR, et al. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31.
CoA	CoA of Quilseconazole

Smiles:	O[C@@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=N3)F


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