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Product Information:

PYCR1-IN-1

PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects .

Cat. No.: EX-A16646    Purity: >98%
Chemical
Chemical structure of PYCR1-IN-1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg100In-stock
250mg220In-stock
500mg352In-stock
1g583In-stock
5g1685In-stock
10g2498In-stock


CAS No.709-85-3
Purity>98%
FormulaC11H12BrN
Mol Weight238.124
ColorColorless to light yellow
StateLiquid (Density: 1.3
SolubilityDMSO : 100 mg/mL
Shelf Life>2 years if stored properly
Storage4°C, stored under nitrogen
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Kirsty Milne, et al. A fragment-like approach to PYCR1 inhibition. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2626-2631.

[2].Forlani G, et al., Phenyl-substituted aminomethylene-bisphosphonates inhibit human P5C reductase and show antiproliferative activity against proline-hyperproducing tumour cells. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1248-1257.

CoACoA of PYCR1-IN-1
Smiles:CN(CC#C)CC1=CC=C(C=C1)Br

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