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Product Information:

Pumosetrag

Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.

Cat. No.: EX-A10274    Purity: >98%
Chemical
Chemical structure of Pumosetrag


For research only, Do not use for Human!

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SynonymsMKC-733
Synonyms 2DDP-733
CAS No.153062-94-3
Purity>98%
FormulaC15H17N3O2S
Mol Weight303.379
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO/H2O
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Chetty N, et al. Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract. Pharmacology. 2008;81(2):104-9. Epub 2007 Oct 19.

[2]. Coleman NS, et al. Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans. Aliment Pharmacol Ther. 2003 Nov 15;18(10):1039-48.

CoACoA of Pumosetrag
Smiles:O=C(C1=CNC(C=CS2)=C2C1=O)N[C@@H]3C4CCN(CC4)C3

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