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Product Information:

PTPN22-IN-1

PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 µM; Ki=0.50 µM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses

Cat. No.: EX-A13804    Purity: >98%
Chemical
Chemical structure of PTPN22-IN-1


For research only, Do not use for Human!

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CAS No.2580935-57-3
Purity>98%
FormulaC26H21N3O5
Mol Weight455.462
ColorWhite to yellow
StateSolid
SolubilityDMSO : 5 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years, 4°C, 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Elizabeth Jaffee, et al. Targeting ptpn22 in cancer therapy. WO2021007491A1.

CoACoA of PTPN22-IN-1
Smiles:O=C1C2=CC(NC([C@H](C)NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=O)=CC=C2NC=C1C(O)=O

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