PTP1B-IN-24

PTP1B-IN-24 (Compound 9) is a reversible PTP1B inhibitor with an IC50 value of 1.4 μM, and PTP1B-IN-24 can enhance the thermal stability of PTP1B. PTP1B-IN-24 can restore PA induced insulin resistance by increasing the phosphorylation levels of IRS1 and AKT.


Cat. No.: EX-A13890	Purity: >98%

	Chemical structure of PTP1B-IN-24

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	498	In-stock
25mg	850	In-stock
50mg	1550	In-stock

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CAS No.	2221707-61-3
Purity	>98%
Formula	C22H16N2O5S
Mol Weight	420.438
Color	White to light yellow
State	Solid
Solubility	DMSO : 10 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zheng Y, et al. New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation. Bioorg Chem. 2024 Feb;143:106985.
CoA	CoA of PTP1B-IN-24

Smiles:	O=C(S/1)N(CC(NC2=CC=C(C)C=C2)=O)C(C1=C\C3=COC4=CC=CC=C4C3=O)=O


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