PT-179

PT-179 is a selective molecular glue and thalidomide derivative, binds CRBN with a Kd of 587 nM, does not induce degradation of known pomalidomide neosubstrates.


Cat. No.: EX-A8803	Purity: >98%

	Chemical structure of PT-179

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	335	in_stock
5g	1006	in_stock

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Synonyms	PT 179
Synonyms 2	PT179
CAS No.	2924858-25-1
Purity	>98%
Formula	C17H17N3O5
Mol Weight	343.334
Color	Light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mercer JAM, DeCarlo SJ, Roy Burman SS, et al. Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science. 2024;383(6688):eadk4422. doi:10.1126/science.adk4422
Data Sheet	Data sheet of PT-179
CoA	CoA of PT-179
SDS	SDS of PT-179

Smiles:	O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(N4CCOCC4)=C3)=O


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