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Product Information:

Protohypericin

Protohypericin is a compound that can be extracted from Hypericum perforatum. Protohypericin has low photocytotoxicity but can be efficiently photoconverted into Hypericin with high phototoxicity under visible light. Protohypericin can be used in cancer research .

Cat. No.: EX-A15597    Purity: >98%
Chemical
Chemical structure of Protohypericin


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg450in-stock
100mg650in-stock
250mg1050in-stock
500mg1650in-stock
1g2550in-stock


CAS No.548-03-8
Purity>98%
FormulaC30H18O8
Mol Weight506.4591
ColorPurple to black
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, protect from light; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kamuhabwa AR, et al. In vitro transport and uptake of protohypericin and hypericin in the Caco-2 model. Int J Pharm. 1999 Oct 15;188(1):81-6./p>

[2]. Delaey EM, et al. Photocytotoxicity of protohypericin after photoconversion to hypericin. Planta Med. 1999 Dec;65(8):719-22.

[3]. Liu X, et al. Tumor necrosis targeted radiotherapy of non-small cell lung cancer using radioiodinated protohypericin in a mouse model. Oncotarget. 2015 Sep 22;6(28):26400-10.

[4]. Baugh SF. Simultaneous determination of protopseudohypericin, pseudohypericin, protohypericin, and hypericin without light exposure. J AOAC Int. 2005 Nov-Dec;88(6):1607-12.

CoACoA of Protohypericin
Smiles:O=C1C2=C(O)C=C(C=C2C3=C4C=5C=C(C=C(O)C5C(=O)C6=C(O)C=C(O)C(C=7C(O)=CC(O)=C1C73)=C64)C)C

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