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Product Information:

PROTAC LRRK2 Degrader-4

PROTAC LRRK2 Degrader-4 is a PROTAC LRRK2 degrader with a DC50 of 0.79 nM. PROTAC LRRK2 Degrader-4 can be used for research in Parkinson’s disease and inflammation .

Cat. No.: EX-A16025    Purity: >98%
Chemical
Chemical structure of PROTAC LRRK2 Degrader-4


For research only, Do not use for Human!

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CAS No.2839664-99-0
Purity>98%
FormulaC45H56N10O5
Mol Weight816.9901
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Renner, A. C., et al. RRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration. ACS Med. Chem. Lett.

CoACoA of PROTAC LRRK2 Degrader-4
Smiles:O=C1C2=CC=C(C(OC)=C2CN1C3C(=O)NC(=O)CC3)N4CCC(CN5CCN(CC5)CC6CCN(C7=NC=NC(=C7)C8=NNC=9C=CC(OC%10(C)CC%10)=CC89)CC6)CC4

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