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Product Information:

PROTAC K-Ras Degrader-4

PROTAC K-Ras Degrader-4 (compound I-27) is a PROTAC that can effectively degrade K-Ras. PROTAC K-Ras Degrader-4 can be used in cancer research.

Cat. No.: EX-A9933    Purity: >98%
Chemical
Chemical structure of PROTAC K-Ras Degrader-4


For research only, Do not use for Human!

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CAS No.2938169-99-2
Purity>98%
FormulaC50H60N12O6S2
Mol Weight989.218
Colorwhite to light yellow
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Popow J, et al. Targeting cancer with small-molecule pan-KRAS degraders. Science. 2024 Sep 20;385(6715):1338-1347.

CoACoA of PROTAC K-Ras Degrader-4
Smiles:C[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CN(CCCCOC=6C=C([C@H](C(=O)N7[C@H](C(NCC8=CC=C(C=C8)C9=C(C)N=CS9)=O)C[C@@H](O)C7)C(C)C)ON6)CCC5

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