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Product Information:

PROTAC IRAK3 degrade-1

PROTAC IRAK3 degrade-1 (compound 23) is a potent and selective degrader of IRAK3 (IC50 = 5 nM).

Cat. No.: EX-A11374    Purity: >98%
Chemical
Chemical structure of PROTAC IRAK3 degrade-1


For research only, Do not use for Human!

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CAS No.2712600-00-3
Purity>98%
FormulaC47H63N11O6
Mol Weight878.0732
 
 
Reference:  

[1]. Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473.

CoACoA of PROTAC IRAK3 degrade-1
Smiles:O=C1C2=CC(N3CCN(CC3)CCC4CCN(CC4)C(CCC(N5CCN([C@@]6([H])CC[C@H](CC6)NC7=NC=NN8C7=C(C(C)C)C=C8)CC5)=O)=O)=CC=C2C(N1C9C(NC(CC9)=O)=O)=O

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