PROTAC EZH2 Degrader-45

PROTAC EZH2 Degrader-45 (compound 61) is a PROTAC protein degrader targeting EZH2 with an IC50 of 22.97 μM in SU-DHL-6 cells. PROTAC EZH2 Degrader-45 can be used for the research of diffuse large b-cell lymphoma .


Cat. No.: EX-A16670	Purity: >98%

	Chemical structure of PROTAC EZH2 Degrader-45

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
25mg	get quote

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CAS No.	3093642-26-0
Purity	>98%
Formula	C62H78N12O8S
Mol Weight	1151.423

Reference:	[1].S Abulkhair H, et al. Therapeutic horizons in the development of PROTAC-based EZH2 inhibitors: recent achievements, comparative analysis, and future perspectives. RSC Adv. 2026;16(4):3034-3056. Published 2026 Jan 14.
CoA	CoA of PROTAC EZH2 Degrader-45

Smiles:	N(CC)(C1=CC(=CC(C(NCC2=C(C)C=C(C)NC2=O)=O)=C1C)C3=CC=C(CN4CCN(C(=O)C5=CN(CC(N[C@H](C(=O)N6[C@H](C(N[C@H](C)C7=CC=C(C=C7)C=8SC=NC8C)=O)C[C@@H](O)C6)C(C)(C)C)=O)N=N5)CC4)C=C3)C9CCOCC9


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