PROTAC ER Degrader-4

PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM .


Cat. No.: EX-A8744	Purity: >98%

	Chemical structure of PROTAC ER Degrader-4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	get quote	Inquire
1g	get quote	Inquire
2g	get quote	Inquire
3g	get quote	Inquire
5g	get quote	Inquire
10g	get quote	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2361114-15-8
Purity	>98%
Formula	C53H67F3N6O8S
Mol Weight	1005.195
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃, sealed storage, away from moisture and light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1.
CoA	CoA of PROTAC ER Degrader-4

Smiles:	CC(C)(F)CN1[C@H](C2=C(C=C(OCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N3[C@@H](C[C@@H](O)C3)C(N[C@H](C4=CC=C(C5=C(N=CS5)C)C=C4)C)=O)=O)=O)C=C2F)F)C6=C(C7=CC=CC=C7N6)C[C@H]1C


		Search