PROTAC EED degrader-2

PROTAC EED degrader-2 is a von Hippel-Lindau-based PROTAC targeting EED with a pKD of 9.27. PROTAC EED degrader-2 is a polycomb repressive complex 2 (PRC2) inhibitor (pIC50=8.11) targeting the EED subunit.


Cat. No.: EX-A11473	Purity: >98%

	Chemical structure of PROTAC EED degrader-2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	600	In-stock
10mg	885	In-stock
25mg	1785	In-stock
50mg	2885	In-stock
100mg	get quote	In-stock
500mg	get quote	In-stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2639882-69-0
Purity	>98%
Formula	C50H58FN11O6S
Mol Weight	960.129
Color	white to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.
CoA	CoA of PROTAC EED degrader-2

Smiles:	N(CC1=C2C(OCC2)=CC=C1F)C=3N4C(C(=CN3)C5=C(C)N=C(CCC(NCCCCC(N[C@H](C(=O)N6[C@H](C(NCC7=CC=C(C=C7)C=8SC=NC8C)=O)C[C@@H](O)C6)C(C)(C)C)=O)=O)C=C5)=NN=C4


		Search