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Product Information:

PROTAC CDK9 Degrader-1

PROTAC CDK9 Degrader-1 is a PROTAC connected by ligands for Cereblon and CDK as a selective CDK9 degrader.

Cat. No.: EX-A8716    Purity: >98%
Chemical
Chemical structure of PROTAC CDK9 Degrader-1


For research only, Do not use for Human!

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CAS No.2118356-96-8
Purity>98%
FormulaC33H35N5O7
Mol Weight613.6603
Colorwhite to off-white
Statesolid powder
SolubilityDMSO : ? 104 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.

CoACoA of PROTAC CDK9 Degrader-1
Smiles:O=C(CC1=CC=C(OCCCCCOC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O)C=C1)NC5=CC(C6CCC6)=NN5

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