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Product Information:

PROTAC AR Degrader-5

PROTAC AR Degrader-5 (compound A46) is a potent AR PROTACs degrader with an IC50 value of 49 nM. PROTAC AR Degrader-5 inhibits sebaceous plaque and induces hair regeneration .

Cat. No.: EX-A10031    Purity: >98%
Chemical
Chemical structure of PROTAC AR Degrader-5


For research only, Do not use for Human!

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CAS No.2703021-51-4
Purity>98%
FormulaC52H54F4N8O7S2
Mol Weight1043.158
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. YouZhi Tong, et al. Bifunctional compound, preparation method therefor, and use thereof. WO2021180160A1.

CoACoA of PROTAC AR Degrader-5
Smiles:S=C1N(C2=C(C(C(F)(F)F)=C(C=C2)C#N)F)C(C(C)(N1C3=CN=C(C4=CC=C(C=C4)OCCCCOCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@H](C5)O)C(NCC6=CC=C(C7=C(N=CS7)C)C=C6)=O)=O)=O)C=C3)C)=O

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