Pro-Dasatinib

Pro-Dasatinib (compound 2j), an amino acid analog of Dasatinib , is a potent Src/Abl kinase inhibitor. Pro-Dasatinib has antiproliferative activity against K652 leukemia cancer cells with an IC50 of 0.21 nM.


Cat. No.: EX-A13311	Purity: >98%

	Chemical structure of Pro-Dasatinib

For research only, Do not use for Human!

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CAS No.	2468065-01-0
Purity	>98%
Formula	C25H29ClN8O2S
Mol Weight	541.068
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Buchappa, G.et al. (2016). Design and Synthesis of Novel Dasatinib Analogues. Asian Journal of Chemistry, 28(6), 1275-1280.
CoA	CoA of Pro-Dasatinib

Smiles:	O=C([C@@H]1CCCN1)N(CC2)CCN2C3=NC(C)=NC(NC4=NC=C(C(NC5=C(C=CC=C5Cl)C)=O)S4)=C3


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