PRMT4-IN-2

PRMT4-IN-2 (compound 55) is a pan-inhibitor of protein arginine methyltransferase (PRMT) with IC50s of 92 nM (PRMT4), 436 nM (PRMT6), 460 nM (PRMT1), 823 nM ( PRMT8), 1.386 μM (PRMT3).


Cat. No.: EX-A13140	Purity: >98%

	Chemical structure of PRMT4-IN-2

For research only, Do not use for Human!

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Purity	>98%
Formula	C23H29N7O
Mol Weight	419.5227
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bhattacharya D, et al. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. Eur J Med Chem. 2023 Nov 15;260:115713..
CoA	CoA of PRMT4-IN-2

Smiles:	O=C(N[C@@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2


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