PRLX-93936 dihydrochloride

PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated Ras pathway and can be used in the study of relapsed or refractory multiple myeloma .


Cat. No.: EX-A10732	Purity: >98%

	Chemical structure of PRLX-93936 dihydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	648	In-stock
500mg	986	In-stock
1g	1572	In-stock

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CAS No.	1094210-96-4
Purity	>98%
Formula	C21H26Cl2N4O2
Mol Weight	437.363
Color	white to off-white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Huang W, et al. Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5239-43. [2]. Voorhees P M, et al. An open-label, dose escalation, multi-center phase 1 study of PRLX 93936, an agent synthetically active against the activated ras pathway, in the treatment of relapsed or relapsed and refractory multiple myeloma[J]. Blood, 2014, 124(21): 2140.
CoA	CoA of PRLX-93936 dihydrochloride

Smiles:	O=C1N(C(CN2CCNCC2)=NC3=C1C=CC=C3)C4=CC=CC=C4OCC.Cl.Cl


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