Pritelivir

Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2.


Cat. No.: EX-A247	Purity: >98%

	Chemical structure of Pritelivir

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	412	In-stock
1g	595	In-stock
2g	985	In-stock
5g	1525	In-stock
10g	2565	In-stock

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Synonyms	BAY 57-1293
CAS No.	348086-71-5
Purity	>98%
Formula	C18H18N4O3S2
Mol Weight	402.491
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ligat G, et al. Identification of Amino Acids Essential for Viral Replication in the HCMV Helicase-PrimaseComplex. Front Microbiol. 2018 Oct 23;9:2483. [2]. Wald A, et al. Helicase-primase inhibitor Pritelivir for HSV-2 infection. N Engl J Med. 2014 Jan 16;370(3):201-10. [3]. Quenelle DC, et al. Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis. Antiviral Res. 2018 Jan;149:1-6.
CoA	CoA of Pritelivir

Smiles:	CN(C(=O)CC1=CC=C(C=C1)C1=NC=CC=C1)C1=NC(C)=C(S1)S(N)(=O)=O


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