PRGL493

PRGL493 is a potent and selective long-chain acyl-CoA synthetase 4 (ACSL4) inhibitor. PRGL493 blocks cell proliferation and tumor growth in both breast and prostate cellular and animal models. PRGL493 is used for cancer research.


Cat. No.: EX-A9099	Purity: >98%

	Chemical structure of PRGL493

For research only, Do not use for Human!

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CAS No.	2479378-45-3
Purity	>98%
Formula	C25H21N7O2
Mol Weight	451.4799

Reference:	[1]. Ana F Castillo, et al. New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis. Cell Mol Life Sci. 2021 Mar;78(6):2893-2910.
CoA	CoA of PRGL493

Smiles:	O=C(C)NC1=NC(C2=CN(C3=CC=CC=C3)N=C2C4=CC=C(C)O4)N5C6=C(C=CC=C6)NC5=N1


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