Preproapelin (61-77) (human, bovine, mouse, rat)

Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ.


Cat. No.: EX-A14188	Purity: >98%

	Chemical structure of Preproapelin (61-77) (human, bovine, mouse, rat)

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	720	In-stock
100mg	1120	Inquire
250mg	1720	Inquire
500mg	2420	Inquire
1g	3320	Inquire

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Synonyms	Apelin Precursor (61-77) (human, bovine, mouse, rat)
Synonyms 2	Apelin-17 (human, bovine, mouse, rat)
CAS No.	217082-57-0
Purity	>98%
Formula	C96H156N34O20S
Mol Weight	2138.547
Color	White to off-white
State	Solid
Solubility	H2O : 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -80°C, 2 years , -20°C, 1 year, Sealed storage, away from moisture; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun. 1998;251(2):471-476. [2]. Medhurst AD, Jennings CA, Robbins MJ, et al. Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J Neurochem. 2003;84(5):1162-1172. [3]. Zou MX, et al. Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett. 2000;473(1):15-18.
CoA	CoA of Preproapelin (61-77) (human, bovine, mouse, rat)

Smiles:	CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@


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