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Product Information:

PPIase-Parvulin Inhibitor

PPIase-Parvulin inhibitor (compound B) is a cell-permeable inhibitor targeting PPIase Pin1 and Par14, with IC50s of 1.5 and 1.0 µM, respectively. PPIase-Parvulin inhibitor has anticancer activity and inhibits the growth and proliferation of mouse embryonic fibroblasts (MEFs) .

Cat. No.: EX-A9587    Purity: >98%
Chemical
Chemical structure of PPIase-Parvulin Inhibitor


For research only, Do not use for Human!

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SynonymsHIC 016C
CAS No.64005-90-9
Purity>98%
FormulaC22H18N2O8
Mol Weight438.3869
ColorOff-white to light yellow
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light, stored under nitrogen; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Uchida T, et al. Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chem Biol. 2003 Jan;10(1):15-24.

CoACoA of PPIase-Parvulin Inhibitor
Smiles:O=C(OCC)CN1C(=O)C2=CC=C3C(=O)N(C(=O)C4=CC=C(C1=O)C2=C34)CC(=O)OCC

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