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Product Information:

Pparδ agonist 5

Pparδ agonist 5, an orally active PPARδ-selective agonist (EC50=0.335 μM), is much greater than that of the prototypical standard GW0742. Pparδ agonist 5 promotes improvements in bone density and microarchitecture in vivo.

Cat. No.: EX-A13684    Purity: >98%
Chemical
Chemical structure of Pparδ agonist 5


For research only, Do not use for Human!

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CAS No.2770846-24-5
Purity>98%
FormulaC23H21F3N2O2S
Mol Weight446.485
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kress BJ, et al. Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis. J Med Chem. 2021;64(10):6996-7032.

CoACoA of Pparδ agonist 5
Smiles:C(N(C)C1=CC(C)=C(/C=C/C(O)=O)C=C1)C=2SC(=NC2C)C3=CC=C(C(F)(F)F)C=C3

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