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Product Information:

POMHEX

POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor.

Cat. No.: EX-A14144    Purity: >98%
Chemical
Chemical structure of POMHEX


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg595In-stock
50mg805In-stock
100mg1105In-stock
250mg1605In-stock
500mg2165In-stock
1g2925In-stock


CAS No.2004714-34-3
Purity>98%
FormulaC17H30NO9P
Mol Weight423.3952
ColorWhite to light yellow
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yu-Hsi Lin, et al. An enolase inhibitor for the targeted treatment of ENO1-deleted cancers. Nat Metab. 2020 Nov 23.

CoACoA of POMHEX
Smiles:CC(C)(C)C(=O)OCOP(=O)(C1CCCN(C1=O)O)OCOC(=O)C(C)(C)C

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