Pomalidomide-PEG3-azide

Pomalidomide-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology . Pomalidomide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.


Cat. No.: EX-A15086	Purity: >98%

	Chemical structure of Pomalidomide-PEG3-azide

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	650	In-stock
500mg	950	In-stock
1g	1650	In-stock
5g	get quote	Inquire
10g	get quote	Inquire
25g	get quote	Inquire

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CAS No.	2267306-15-8
Purity	>98%
Formula	C21H24N6O8
Mol Weight	488.4507
Color	White to yellow
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, stored under nitrogen, away from moisture; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Fangqing Zhang, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
CoA	CoA of Pomalidomide-PEG3-azide

Smiles:	O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)COCCOCCOCCN=[N+]=[N-]


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