PK68

PK68 is a potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis.


Cat. No.: EX-A4768	Purity: >98%

	Chemical structure of PK68

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	500	In-stock
100mg	700	In-stock
250mg	1000	In-stock
500mg	1450	In-stock
1g	1950	In-stock
3g	3950	In-stock

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CAS No.	2173556-69-7
Purity	>98%
Formula	C22H24N4O3S
Mol Weight	424.516
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hou J, et al. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis. Cell Death Dis. 2019 Jun 24;10(7):493.
CoA	CoA of PK68

Smiles:	CC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(S3)NC(=O)C)NC(=O)OC4CCCCC4


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